J Korean Soc Environ Anal Search


Journal of the Korean Society for Environmental Analysis 2016;19(4):225-245.
Application of Target, Suspect, Nontarget Screening Methods based on High Resolution Mass Spectrometry for the Identification of Micropollutants and Their Transformation Products in Aquatic Environments: A Review
고분해능질량분석기 기반의 표적, 추정, 비표적 분석기법을 활용한 수환경 미량오염물질 및 환경변환체 탐색: A review
전준호1, 박나리1, 이선홍2
Micropollutants including pharmaceuticals, personal care products, pesticides, etc., and their transformation products (TP) are widely distributed in environmental media. However, limited information on their occurrence and concentration is available, at least partially due to lack of precise, reliable analytical tools. Recently, highly advanced instrument such as high resolution mass spectrometry (HRMS) has been commercially available and applicable for the detection of micropollutants and TPs. In addition, HRMS relevant screening techniques, suspect and nontarget screening, have been developed and optimized to identify unpredictable and unknown pollutants at trace levels. In this review paper, prior micropollutants and their TPs are suggested via literature survey, and the procedure of target/suspect/nontarget screening for their identification are introduced in detail with technical steps. Finally, the applicability of HRMS-based identification methods is discussed with lessons from previous studies. Considering the accuracy and applicability, suspect/nontarget screening approaches with HRMS are expected to extend our knowledge on micropollutants and TPs under the cover.
Key Words: Micropollutants, Transformation products, LC-HRMS, Suspect screening, Nontarget screening, Unknown contaminants


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